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ACUTE EXPOSURE INFORMATION

  1. Chloromethyl methyl ether is irritating to the eyes, skin, and mucous membranes. Signs and symptoms following exposure may include sore throat, cough, wheezing, pulmonary congestion, bronchial secretions, blood stained sputum, weight loss, fever, and chills. Pulmonary edema, pneumonia, and skin burns and necrosis may occur. Pulmonary edema and hemorrhage and necrotizing bronchitis have occurred in experimental animals.
  1. Inhalation may cause death from noncardiogenic pulmonary edema or chemical pneumonitis. Chronic bronchitis, lung cancer, and possibly laryngeal cancer are associated with chronic inhalation exposure to chloromethyl ethers.
  1. Chloromethyl methyl ether is a suspected human carcinogen; oat cell lung cancer has been associated with chronic exposure. Its contaminant, bis-chloromethyl ether, is also a known human carcinogen.
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