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ACUTE EXPOSURE INFORMATION

  1. Fensulfothion is an organophosphate compound. The following are symptoms from organophosphates in general, which are due to the anticholinesterase activity of this class of compounds. All of these effects may not be documented for fensulfothion, but could potentially occur in individual cases.
    1. Fensulfothion causes typical anticholinesterase poisoning. Dermal contact can cause skin irritation.
  1. MUSCARINIC (PARASYMPATHETIC) EFFECTS - may include bradycardia, bronchospasm, bronchorrhea, salivation, lacrimation, diaphoresis, vomiting, diarrhea, and miosis. NICOTINIC (SYMPATHETIC AND MOTOR) EFFECTS may include tachycardia, hypertension, fasciculations, muscle cramps, weakness, and RESPIRATORY PARALYSIS. CENTRAL EFFECTS may include CNS depression, agitation, confusion, delirium, coma, and seizures.
  1. Children may exhibit different predominant signs and symptoms than adults: CNS depression, stupor, flaccidity, dyspnea, and coma are the most common signs in children.
  1. Organophosphate insecticides have been reported to cause outbreaks of non-bacterial foodborne poisoning presenting as a cholinergic syndrome (Greenaway & Orr, 1996).
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