RightAnswer Knowledge Solutions Search Results for 75-21-8

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ACUTE EXPOSURE INFORMATION

1. Early signs and symptoms of exposure to ethylene oxide (ETO) may include eye, nose, and throat irritation and noticing a sweet or peculiar taste in the mouth.

2. Delayed effects may include headache, nausea, vomiting, diarrhea, abdominal pain, dyspnea, cough, weakness, lethargy, numbness, incoordination and vertigo. Acute effects such as pneumonia, pulmonary edema, respiratory failure, asthma, cardiac arrhythmias, seizures, allergic reaction, paralysis and coma may also be seen.

3. Direct contact with the eye can cause severe ocular damage. Direct dermal contact with the gas or liquid ethylene oxide can cause blistering, severe chemical burns and tissue necrosis. Evaporation of the liquid from the skin may cause frostbite.

4. Occupational exposure to ethylene oxide may be linked with spontaneous abortions and other adverse reproductive effects. ETO is known to cause cancer in laboratory animals and is a probable human carcinogen. Leukemia and non-Hodgkin's lymphoma have been primarily associated with ETO. Cases of Hodgkin's disease, stomach, breast and pancreatic cancer, lymphosarcoma and reticulosarcoma have also been reported.

5. CNS and musculoskeletal abnormalities have been reported in the offspring of laboratory animals.

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