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ACUTE EXPOSURE INFORMATION

  1. Pentachlorophenol is toxic by ingestion, inhalation, and skin absorption; abuse may be fatal. This compound readily penetrates the skin. The pulmonary route of exposure may be most toxic to adults.
  1. Prolonged or frequent contact with either solution or dust may cause dermatitis or systemic symptoms including damage to the circulatory system and the heart. Hyperpyrexia and cardiac failure are common reactions during overdose.
  1. ACUTE poisoning is marked by dermatitis, weakness, tachypnea, polyuria followed by oliguria, seizures, and rapidly progressing coma in severe cases. Hyperthermia is the major factor leading to death following a fatal exposure in humans. Death may occur within a few hours following absorption.
  1. CHRONIC poisoning may produce anorexia, weight loss, weakness, dizziness, headache and anxiety.
  1. Serious exposures may leave sequelae including impaired autonomic nervous function, circulation, visual change, and an acute type of scotoma.
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