RightAnswer Knowledge Solutions Search Results for Chlorophacinone

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ACUTE EXPOSURE INFORMATION

1. In massive overdose, these agents have produced rapid and persistent hypoprothrombinemia and associated bleeding diathesis. Chlorophacinone produces especially prolonged periods of hypocoagulability. Once coagulation defects occur, they may persist for 6 weeks to many months. Because it has an elimination half-life of several days, daily exposures would produce cumulative toxicity. No chronic data were found for chlorophacinone in humans, however.

2. Cardiopulmonary injury and neurologic toxicity have been reported with the indandiones in animals but not humans.

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